Evidence for Camel-to-Human Transmission of MERS Coronavirus
Identifieur interne : 001E50 ( Main/Exploration ); précédent : 001E49; suivant : 001E51Evidence for Camel-to-Human Transmission of MERS Coronavirus
Auteurs : Esam I. Azhar [Arabie saoudite] ; Sherif A. El-Kafrawy [Arabie saoudite] ; Suha A. Farraj [Arabie saoudite] ; Ahmed M. Hassan [Arabie saoudite] ; Muneera S. Al-Saeed [Arabie saoudite] ; Anwar M. Hashem [Arabie saoudite] ; Tariq A. Madani [Arabie saoudite]Source :
- The New England journal of medicine [ 0028-4793 ] ; 2014.
Descripteurs français
- Pascal (Inist)
- Wicri :
English descriptors
Abstract
We describe the isolation and sequencing of Middle East respiratory syndrome coronavirus (MERS-CoV) obtained from a dromedary camel and from a patient who died of laboratory-confirmed MERS-CoV infection after close contact with camels that had rhinorrhea. Nasal swabs collected from the patient and from one of his nine camels were positive for MERS-CoV RNA. In addition, MERS-CoV was isolated from the patient and the camel. The full genome sequences of the two isolates were identical. Serologic data indicated that MERS-CoV was circulating in the camels but not in the patient before the human infection occurred. These data suggest that this fatal case of human MERS-CoV infection was transmitted through close contact with an infected camel.
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">We describe the isolation and sequencing of Middle East respiratory syndrome coronavirus (MERS-CoV) obtained from a dromedary camel and from a patient who died of laboratory-confirmed MERS-CoV infection after close contact with camels that had rhinorrhea. Nasal swabs collected from the patient and from one of his nine camels were positive for MERS-CoV RNA. In addition, MERS-CoV was isolated from the patient and the camel. The full genome sequences of the two isolates were identical. Serologic data indicated that MERS-CoV was circulating in the camels but not in the patient before the human infection occurred. These data suggest that this fatal case of human MERS-CoV infection was transmitted through close contact with an infected camel.</div>
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